01
Cultivate
The starting material is a 20th-generation cultured botanical of Aloe barbadensis Miller. The plant is grown for the inner-leaf polysaccharides that become the extract.

The process
Three steps sit between the plant and the finished dietary supplement: cultivate, extract, stabilize. The cream uses stabilized acemannan as one ingredient in a plant-based moisturizer.
01
The starting material is a 20th-generation cultured botanical of Aloe barbadensis Miller. The plant is grown for the inner-leaf polysaccharides that become the extract.
02
An alcohol precipitation process concentrates the long-chain polysaccharides from the aloe. The aim is a high-molecular-weight acemannan fraction rather than a diluted juice or gel.
03
The finished material is prepared to retain a high-molecular-weight profile — described as 1 million to 10 million Daltons — along with mannose, glucomannans, oligosaccharides, mucopolysaccharides, glycoproteins, glycolipids, and trace plant minerals.
Independent literature
Researchers have published work on acemannan, including its role in macrophage activity in laboratory studies.
These papers study the ingredient in laboratory and animal models.
Independent literature · PubMed
Independent literature search · PubMed
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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